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Azure IS4000 Sapphire FL Biomolecular Imager
£ 43,402.17 ex. VAT
Sapphire FL Biomolecular Imager
Precise quantitation of nucleic acids and proteins, from in vitro molecular assays to in vivo imaging
Available on backorder
Key Features
Flexibility with uncompromising performance
The Sapphire FL is the second generation Sapphire and ultimate biomolecular imager for FLEXIBILITY. With customizable and user-changeable laser and filter modules, it easily adapts to a lab’s changing needs and advancing research. The Sapphire FL offers customizable and user-changeable optical modules, 5–1000 μm resolution scans, a Z-plane range from -1.0 to +6 mm, five anesthesia ports for imaging living animals, chemiluminescence detection through a Chemiluminescence Module, and much more.
Unlimited Laser and Filter Wavelength combinations
It features a unique, patent-pending design of interchangeable and customizable laser and filter modules, enabling a virtually infinite number of spectral combinations. A broad range of excitation and emission wavelengths, as well as phosphor imaging, are supported.
The Sapphire FL is the only biomolecular scanner in its class that reaches into the UV spectrum, allowing multiplexing of UVÂ dyes with dyes in the NIR. Using the 375 Standard Optical Module, it is able to image common DNA stains, such as Dapi and Hoechst.
Application Flexibility
The flexibility of the Sapphire FL guarantees you the freedom to confidently choose the best dyes and chemistry for any experiment. Custom optical modules can excite any dye at its peak, resulting in the highest possible signal for any fluorophore.
In addition to fluorescence, the Sapphire FL also excels at imaging phosphor screens and chemiluminescence using the optional Chemiluminescence Module.
Sensitive Fluorescent Detection
High sensitivity allows femtogram detection of proteins labeled with common fluorescent dyes.
No other system on the market matches the Sapphire FL’s coverage across the fluorescent spectrum. Extend your reach into the UV spectrum with the 375 Standard Optical Module.
Total Flexibility with Phosphor Imaging
The Sapphire FL is a compact phosphor imager that incorporates exceptional visible fluorescent and near infra-red (NIR) scanning, along with true chemiluminescent and white light imaging, to make it a true lab workhorse.
It is one of only two scanning systems in its class that offers phosphor imaging, a high sensitivity assay that requires radioactivity. The Sapphire FL is able to scan storage phosphor screens with exceptional dynamic range and image quality, thanks to the use of laser excitation and photon multiplier tube (PMT) detection.
In Vivo Imaging
The Sapphire FL imager makes imaging of live animals possible. Living mice or other small animals can be fluorescently imaged under anesthesia using any of the five built-in anesthesia ports.
The wide imaging platform can accommodate specimens with depth (up to 4 cm), allowing small animals, plants, petri dishes, and other large biological samples to be imaged.
Distinguish between Subtle Differences in Expression with Extended Dynamic Range (EDR)
Extended dynamic range allows you to image both bright and weak bands without experiencing saturation. This is ideal for the samples that feature strong and weak expressing proteins.
EDR extends dynamic range to 24 bits of data.
Adjustable Focus
Some samples can be imaged on the glass (Western blots), while others are raised above the glass surface (96-well plates). The Sapphire FL can image them all.
Some samples have multiple focal points within them, such as tissue slides and organs. The Sapphire FL can image those too.
It offers a 7mm software-controlled adjustable focal plane, so you can scan your sample at multiple depths to ensure you see all your data has to offer.
5-micron Resolution
The Sapphire FL scans between 5 – 1000 µm resolution to ensure clear visualization of detailed samples. Image complex and minute samples, including tissue and microarray slides, with accuracy. Triage multiple slides at high resolution before microscopic analysis.
Chemiluminescent Imaging When You Need It
An optional Chemiluminescence Module adds high-resolution, quantitative chemiluminescence and visible imaging.
It allows you to express proteins with femtogram sensitivity and gives you the ability to capture color marker images.
| Parameter | Value |
|---|---|
| Weight | 43.5 kg |
| Product type | High Resolution Scanner |
| Memory | 512GB NVMe SSD |
| Brand | Azure Biosystems |
Optional Accessories
| Product | Price | |
|---|---|---|
Azure Compact Workstation with Embedded Monitor for Sapphire FL. Compact workstation with a built-in monitor, running Windows and configured with Sapphire Capture Software for operating the Sapphire FL Biomolecular Imager. Includes power cable, embedded keyboard and touchpad.
SKU: IS2011 |
£ 0.00 |
|
Azure Desktop Workstation with External High-Resolution Monitor for Sapphire FL. Premium high-performance desktop workstation with a large 27″ high-resolution 4K monitor, running Windows and configured with Sapphire Capture Software for operating the Sapphire FL Biomolecular Imager. Includes power and monitor cables, external keyboard and mouse.
SKU: IS2012 |
£ 0.00 |
|
Azure 375 Standard Optical Module. Includes 375 nm laser and 452/45 filter
SKU: IS4030 |
£ 12,967.39 |
|
Azure 450 Standard Optical Module. Includes 450 nm laser and 494/34 filter
SKU: IS4031 |
£ 10,793.48 |
|
Azure 488 Standard Optical Module. Includes 488 nm laser and 513/17 filter
SKU: IS4001 |
£ 10,793.48 |
|
Azure 488 (YFP) Standard Optical Module. Includes 488 nm laser and 534/20 filter
SKU: IS4032 |
£ 10,793.48 |
|
Azure 532 Standard Optical Module. Includes 532 nm laser and 572/28 filter
SKU: IS4002 |
£ 10,793.48 |
|
Azure 532 (Propidium) Standard Optical Module. Includes 532 nm laser and 624/40 filter
SKU: IS4033 |
£ 10,793.48 |
|
Azure 638 Standard Optical Module. Includes 638 nm laser and 676/37 filter
SKU: IS4003 |
£ 10,793.48 |
|
Azure 658 Standard Optical Module. Includes 658 nm laser and 710/40 filter
SKU: IS4057 |
£ 10,793.48 |
|
Azure 685 Standard Optical Module. Includes 685 nm laser and 720/24 filter
SKU: IS4004 |
£ 10,793.48 |
|
Azure 730 Standard Optical Module. 730 Standard Optical Module
SKU: IS4066 |
£ 10,793.48 |
|
Azure 784 Standard Optical Module. Includes 784 nm laser and 829/62 filter
SKU: IS4005 |
£ 10,793.48 |
|
Azure Phosphor Imaging Standard Optical Module. Adds Phosphor Imaging to Sapphire FL
SKU: IS4006 |
£ 14,416.67 |
|
Azure Sapphire FL 375 nm Laser. 375 nm laser module (not including emission filter)
SKU: IS4023 |
£ 11,518.12 |
|
Azure Sapphire FL 450 nm Laser. 450 nm laser module (not including emission filter)
SKU: IS4024 |
£ 10,068.84 |
|
Azure Sapphire FL 488 nm Laser. 488 nm laser module (not including emission filter)
SKU: IS4025 |
£ 10,068.84 |
|
Azure Saphire 488 nm (YFP) laser module (not including emission filter)
SKU: IS4055 |
£ 10,068.84 |
|
Azure Sapphire FL 532 nm Laser. 532 nm laser module (not including emission filter)
SKU: IS4026 |
£ 10,068.84 |
|
Azure Sapphire FL 638 nm Laser. 638 nm laser module (not including emission filter)
SKU: IS4027 |
£ 10,068.84 |
|
Azure Sapphire FL 658 nm Laser. 658 nm laser module (not including emission filter)
SKU: IS4059 |
£ 10,068.84 |
|
Azure Sapphire FL 685 nm Laser. 685 nm laser module (not including emission filter)
SKU: IS4028 |
£ 10,068.84 |
|
Azure Saphire 730 nm laser module (not including emission filter)
SKU: IS4067 |
£ 10,068.84 |
|
Azure Sapphire FL 784 nm Laser. 784 nm laser module (not including emission filter)
SKU: IS4029 |
£ 10,068.84 |
|
Azure Sapphire FL 424/SP Filter. 424/SP nm filter
SKU: IS4056 |
£ 2,822.46 |
|
Azure Sapphire FL 452 Filter. 452/45 nm filter
SKU: IS4008 |
£ 2,822.46 |
|
Azure Sapphire FL 494 Filter. 494/34 nm filter
SKU: IS4011 |
£ 2,822.46 |
|
Azure Sapphire FL 513 Filter. 513/17 nm filter
SKU: IS4012 |
£ 2,822.46 |
|
Azure Sapphire FL 534 Filter. 534/20 nm filter
SKU: IS4010 |
£ 2,822.46 |
|
Azure Sapphire FL 572 Filter. 572/28 nm filter
SKU: IS4049 |
£ 2,822.46 |
|
Azure Sapphire FL 624 Filter. 624/40 nm filter
SKU: IS4013 |
£ 2,822.46 |
|
Azure Sapphire FL 676 Filter. 676/37 nm filter
SKU: IS4009 |
£ 2,822.46 |
|
Azure Sapphire FL 710 Filter. 710/40 nm filter
SKU: IS4058 |
£ 2,822.46 |
|
Azure Sapphire FL 720 Filter. 720/24 nm filter
SKU: IS4046 |
£ 2,822.46 |
|
Azure Sapphire FL 809 Filter. 809/81 nm filter
SKU: IS4068 |
£ 2,822.46 |
|
Azure Sapphire FL 829 Filter. 829/62 nm filter
SKU: IS4047 |
£ 2,822.46 |
|
Azure Sapphire FL Advanced Chemiluminescence Module. Adds Advanced Chemiluminescence Module to Sapphire FL (AZI300-01)
SKU: IS4060 |
£ 21,655.11 |
|
Azure Sapphire FL Chemiluminescence Module. Adds Basic Chemiluminescence Module to Sapphire FL (CS1000)
SKU: IS4007 |
£ 10,108.70 |
|
Azure Sapphire FL Ethernet Connection Kit. Ethernet connection kits for the Basic Chemiluminescence Module, contains 7 Foot Cat6 (UTP) Ethernet Cable and 4 port Netgear Ethernet switch
SKU: IS4052 |
£ 0.00 |
|
Azure Sapphire Mat. Designed for flattening membranes against the glass surface
SKU: IS1010 |
£ 0.00 |
|
Azure Azure DensitoMetrics. Sapphire densitometry package for Sapphire Biomolecular Imager with a green channel (520 nm laser).
SKU: IS2018 |
£ 1,445.65 |
|
Azure Sapphire FL Slide Holder. Fixture designed to hold up to 15 standard microscope slides for use with the Sapphire FL.
SKU: IS4053 |
£ 2,090.58 |
|
Azure Sapphire FL Plate Holder. Fixture designed to hold up to four standard 96-well plates with optically clear bottoms for use with the Sapphire FL.
SKU: IS4054 |
£ 2,090.58 |
|
Azure Azure Test Target (Black). Azure Test Target with black background and transparent areas around bands and logo
SKU: IS4069 |
£ 0.00 |
|
Azure Sapphire Eraser. Dedicated instrument for erasing storage phosphor screens (imaging plates). LED light source, easy-to-use drawer design and interface (fits up to 25 x 25 cm storage phosphor screens)
SKU: IS1015 |
£ 5,793.48 |
|
Azure Cassette for Storage Phosphor Screen. Exposure Cassette for Storage Phosphor Screen
SKU: IS1012 |
£ 0.00 |
|
Azure Storage Phosphor Screen – MS. Multipurpose screen for phosphor imaging (20 x 25 cm)
SKU: IS1011 |
£ 0.00 |
|
Azure Storage Phosphor Screen – SR. High resolution screen for phosphor imaging (20 x 25 cm)
SKU: IS1021 |
£ 0.00 |
|
Azure Anesthesia Nose Cone. Set of five 7mm anesthesia nose cones for a tight fit with laboratory mice. For use with Anesthesia Tubing (IS4051).
SKU: IS4050 |
£ 0.00 |
|
Azure Anesthesia Tubing. 18 inches of tubing with luer fittings for use with 7mm Anesthesia Nose Cones (IS4050). Compatible with low-flow electronic vaporizers and the Sapphire FL.
SKU: IS4051 |
£ 0.00 |
|
Azure AzureSpot Pro. Analysis of 1D gels and Western blots, band analysis, array analysis, colony counting. PC and Mac compatible. Electronic License with 4 computer installations.
SKU: AC1078 |
£ 1,050.72 |
|
Azure AzureSpot Pro 20. Analysis of 1D gels and Western blots, band analysis, array analysis, colony counting. PC and Mac compatible. Electronic License with 20 computer installations.
SKU: AC1132 |
£ 0.00 |
|
Azure SameSpots 2D Analysis Software. Compact workstation with a built-in monitor, running Windows and configured with Sapphire Capture Software for operating the Sapphire FL Biomolecular Imager. Includes power cable, embedded keyboard and touchpad.
SKU: IS1013 |
£ 0.00 |
|
Azure SpotMap Analysis Software. SpotMap software package is unique and easy-to-use software specifically designed for analysis of HCP (host cell protein) coverage for biologic product characterisation, process development/optimisation and HCP antibody assay and impurity profiling. Electronic License with 1 computer installation.
SKU: IS1014 |
£ 0.00 |
|
AzureSpot Pro GxP. Analysis of 1D Gels and Western blots. Supplies compliance with 21CFR Part11. Includes IQ OQ for the analysis software. PC compatible. Electronic License with 1 Software Installation.
SKU: AC1077 |
£ 0.00 |
|
Azure SpotMap GxP. SpotMap software package unique and easy-to-use software specifically designed for analysis of HCP (host cell protein) coverage for biologic product characterization, process development/optimization and HCP antibody assay & impurity profiling. Assists compliance with 21CFR Part11. Includes IQ OQ. Electronic License with 1 computer installation.
SKU: AC1075 |
£ 0.00 |
|
Azure Sapphire FL IQOQ Documentation. IQOQ documentation for Sapphire FL Biomolecular Imager and associated fluorescent optical modules. Includes Procedure, Checklist and Logbook, Azure Test Targets, and Certificates. Excludes service.
SKU: IS4020 |
£ 0.00 |
|
Azure Sapphire FL IQOQ Service. Service for performing IQOQ procedure for Sapphire FL Biomolecular Imager
SKU: IS4021 |
£ 0.00 |
|
Azure Installation and Training for Sapphire FL. Installation and training on Sapphire FL Imager with an application specialist
SKU: IS2025 |
£ 0.00 |
|
Azure Sapphire FL Demo Case. Demo case for Sapphire FL
SKU: IS4034 |
£ 0.00 |
|
Azure Additional 1-Year Warranty Sapphire FL ? International. Extends standard warranty by 1 year for the Sapphire FL imager
SKU: IS4042 |
£ 0.00 |
|
Azure Sapphire FL Contract Reinstatement Fee. Flat fee to bring a system back under Contract. Does not include cost of contract
SKU: IS4045 |
£ 0.00 |
|
SKU: IS4032
SKU: IS4033
SKU: IS4006
SKU: IS4023
SKU: IS4024
SKU: IS4025
SKU: IS4026
SKU: IS4027
SKU: IS4059
SKU: IS4028
SKU: IS4029
